Searchable abstracts of presentations at key conferences in endocrinology

ea0063p230 | Pituitary and Neuroendocrinology 1 | ECE2019

The role of interleukin-1 in the dynamics of exercise-induced copeptin

Popovic Milica , Timper Katharina , Seelig Eleonora , Nordmann Thierry , Erlanger Tobias , Donath Marc , Christ-Crain Mirjam

Background: The goal of this project was to identify non-osmotic stimuli of arginine vasopressin (AVP) release during exercise. Non-osmotic AVP release can lead to severe hyponatremia in otherwise healthy marathon runners.Interleukin-1 (IL-1) increases during exercise and was shown to induce AVP in animal models. We here therefore investigated whether copeptin (a surrogate marker for AVP) increases upon exercise in young and healthy males, and whether this increase is regulate...